Milbemax

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Sale Price without tax $67.50
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SKU: P58 Category:

Milbemax® (Milbemycin Oxime, Praziquantel)

The product information is not intended to provide complete medical information. You should always obtain complete medical information about your veterinary product prescription (including their beneficial medical uses and possible adverse effects) by discussing the appropriate use of any veterinary product directly with the prescribing veterinarian.

Description

Product Type

Milbemax is an oral broad-spectrum anthelmintic tablet for the treatment of mixed infections with roundworms, hookworms and tapeworms, and the prevention of heartworm disease in cats.

Description and Composition

MILBEMAX Film-coated tablets for cats: a tablet containing 16 mg milbemycin oxime and 40 mg praziquantel.

  • Properties

Milbemycin oxime belongs to the group of macrocyclic lactones, isolated from the fermentation of Streptomyces hygroscopicus var.aureolacrimosus. It is active against mites, larval and adult stages of nematodes as well as against larvae of Dirofilaria immitis.

The activity of milbemycin is related to its action on invertebrate neurotransmission: Milbemycin oxime, like avermectins and other milbemycins, increases nematode and insect membrane permeability to chloride ions via glutamate-gated chloride ion channels (related to vertebrate GABAA and glycine receptors). This leads to hyperpolarisation of the neuromuscular membrane and flaccid paralysis and death of the parasite.

Praziquantel is an acylated pyrazino-isoquinoline derivative. Praziquantel is active against cestodes and trematodes. It modifies the permeability for calcium (influx of Ca2+) in the membranes of the parasite inducing an imbalance in the membrane structures, leading to membrane depolarisation and almost instantaneous contraction of the musculature (tetany), rapid vacuolization of the syncytial tegument and subsequent tegumental disintegration (blebbing), resulting in easier expulsion from the gastrointestinal tract or death of the parasite

Indications

MILBEMAX for cats is indicated for the treatment of mixed infections by gastro-intestinal nematodes such as roundworms (Toxocara cati), hookworms (Ancylostoma tubaeforme) and cestodes such as (Dipylidium caninumTaenia spp., Echinococcus spp.).

Prevention of heartworm disease (Dirofilaria immitis) if concomitant treatment against cestodes is indicated.

Dosage and Administration

The product should be administered with or after some food.

MILBEMAX is given orally to cats at the minimal dose rate of 2 mg of milbemycin oxime and 5 mg of praziquantel per kg body weight according to the following table:

Weight of cat

Film-coated tablets for small cats and kittens

Film-coated tablets for cats

0.5 to 1 kg

½ tablet

 

> 1 to 2 kg

1 tablet

 

> 2 to 4 kg

 

½ tablet

> 4 to 8 kg

 

1 tablet

> 8 to 12 kg

 

1½ tablets